Bryan offers about 40 options in 19 major areas. Each student must complete an Application for Major and receive approval from an academic division to be officially enrolled in a major program. This application for major is normally completed during the second semester of the sophomore year, but it may be completed earlier once a student has decided on a major.
 
In addition to course requirements listed on the four-year plans and the catalog, each department requires a senior assessment in the major; and the college requires a variety of core curriculum assessments prior to graduation.

Biblical Studies

Biology

• Foundation Option
• Biology Licensure Option
• Nursing (Vanderbilt "Bridge" Program)

Business Administration

• Management Option
• Economics/Finance Option
• Human Resources Management Option
• Management Information Systems Option
• Economics/Finance & Management Option

Christian Ministry

• Christian Leadership Option
• Pastoral Ministry Option
• Youth Ministry Option

Christian Thought

Communication Studies

• Film and Media Option
• Foundation Option
• Corporate Communication Option
• Journalism Option
• Political Communication Option

Criminal Justice

Education - Elementary & Secondary

English

• Literature Option
• English Licensure Option

Environmental Science

Exercise and Health Science

• Foundation Option
• Physical Education Licensure Option

History

• Foundation Option
• History Licensure Option

Liberal Arts

• Arts & Humanities Option
• Classical Studies Option
• Natural & Mathematical Sciences Option
• Social & Behavioral Sciences Option

Mathematics      

• Foundation Option
• Applied Mathematics and Informatics Option
• Mathematics Licensure Option
• Computer Science Program

Music

• Christian Ministry/Church Music Option
• Contemporary Music Option
• Music Administration Option
• Music Education Instrumental Licensure Option
• Music Education Vocal/General Licensure Option
• Music Ministry/Church Music Option
• Music Technology Option
• Musical Theatre Option
• Piano Pedagogy Option
• Performance Option with a concentration in piano, voice, organ, or instrument

Politics & Government

• Foundation Option
• Economics Option
• Governmental Studies Option
• Law Option
• Political Studies Option

Pre-Professional Programs

• Pre-Law
• Pre-Medicine
• Pre-Pharmacy
• Pre-Veterinarian
• Nursing

Psychology

• Foundation Option
• Psychology Licensure Option

Spanish

• Foundation Option
• Spanish Licensure Option

Theatre